Ralph Abi Hachem, MD, MSc

Program Editor, Rhinology

Assistant Professor of Head and Neck Surgery and Communication Sciences, Duke University

Ralph Abi Hachem, MD, MSc

Ralph Abi Hachem is an Assistant Professor in the Department of Head and Neck Surgery & Communication Sciences at Duke University with a secondary appointment in the Department of Neurosurgery.

He completed his residency in Otolaryngology and Head and Neck Surgery at the University of Miami followed by a fellowship at the Ohio State University in advanced Rhinology and Skull Base Oncology and Surgery. He currently serves as Medical Director of the Duke Skull Base Center and as Fellowship Co-Director of the Rhinology and Endoscopic Skull Base Surgery. His research is focused on sinonasal tumors outcomes, treatment of sinusitis and olfaction neurogenesis. He has published over 35 peer-reviewed articles and edited a textbook on sinonasal disorders.

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Survival outcomes in sinonasal carcinoma with neuroendocrine differentiation: A NCDB analysis
Am J Otolaryngol. 2021 Mar-Apr;42(2):102851. doi: 10.1016/j.amjoto.2020.102851. Epub 2020 Dec 17.
Sinus Irrigation Penetration After Proposed Modified Draf IIa Technique in a Side-to-Side Cadaveric Model
Am J Rhinol Allergy. 2021 Jul;35(4):487-493. doi: 10.1177/1945892420969141. Epub 2020 Oct 21.
Survival Outcomes in Sinonasal Poorly Differentiated Squamous Cell Carcinoma
Laryngoscope. 2021 Apr;131(4):E1040-E1048. doi: 10.1002/lary.29090. Epub 2020 Sep 22.
Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia
Sci Adv. 2020 Jul 31;6(31):eabc5801. doi: 10.1126/sciadv.abc5801. Epub 2020 Jul 24.
General Complications after Endoscopic Sinus Surgery in Smokers: A 2005-2016 NSQIP Analysis
Ann Otol Rhinol Laryngol. 2021 Apr;130(4):350-355. doi: 10.1177/0003489420952481. Epub 2020 Aug 20.
Sinonasal Squamous Cell Carcinoma Outcomes: Does Treatment at a High-Volume Center Confer Survival Benefit?
Otolaryngol Head Neck Surg. 2020 Nov;163(5):986-991. doi: 10.1177/0194599820935395. Epub 2020 Jun 30.
The use of balloon dilation in revision sinus surgery
Int Forum Allergy Rhinol. 2020 Oct;10(10):1158-1164. doi: 10.1002/alr.22571. Epub 2020 May 29.
Novel Application of Steroid Eluting Stent in Petrous Apex Cholesterol Granuloma
J Neurol Surg B Skull Base. 2019 Oct;80(5):500-504. doi: 10.1055/s-0038-1675751. Epub 2018 Nov 27.
Sinonasal Quality of Life Outcomes After Extended Endonasal Approaches to the Skull Base
J Neurol Surg B Skull Base. 2019 Aug;80(4):416-423. doi: 10.1055/s-0038-1675592. Epub 2018 Nov 12.
Symptom Profile of Chronic Rhinosinusitis Versus Obstructive Sleep Apnea in a Tertiary Rhinology Clinic
Ann Otol Rhinol Laryngol. 2019 Oct;128(10):963-969. doi: 10.1177/0003489419851527. Epub 2019 May 22.
Factors associated with opioid use after endoscopic sinus surgery
Laryngoscope. 2019 Aug;129(8):1751-1755. doi: 10.1002/lary.27921. Epub 2019 Mar 12.
Decreased Antibiotic Utilization After Sinus Surgery in Cystic Fibrosis Patients With Lung Transplantation
Am J Rhinol Allergy. 2019 Jul;33(4):354-358. doi: 10.1177/1945892419830624. Epub 2019 Feb 20.
Preoperative Management of Chronic Rhinosinusitis Prior to Office Balloon Sinus Dilation: A 2011-2014 MarketScan® Analysis
Am J Rhinol Allergy. 2019 Jul;33(4):347-353. doi: 10.1177/1945892419829335. Epub 2019 Feb 7.
Factors Associated with Revision Surgery after Balloon Sinuplasty
Otolaryngol Head Neck Surg. 2019 Apr;160(4):734-739. doi: 10.1177/0194599818813044. Epub 2018 Nov 20.
A systematic review on sinonasal mixed adenoneuroendocrine carcinoma
Int Forum Allergy Rhinol. 2021 Sep;11(9):1391-1394. doi: 10.1002/alr.22811. Epub 2021 May 19.
Healthcare Resource Utilization for Chronic Rhinosinusitis in Older Adults
Healthcare (Basel). 2021 Jun 25;9(7):796. doi: 10.3390/healthcare9070796.
Endoscopic Sinus Surgery for Cystic Fibrosis: Variables Influencing Sinonasal and Pulmonary Outcomes
Am J Rhinol Allergy. 2022 May;36(3):307-312. doi: 10.1177/19458924211059606. Epub 2021 Nov 20.
Olfactory-Specific Quality of Life Outcomes after Endoscopic Endonasal Surgery of the Sella
Allergy Rhinol (Providence). 2021 Oct 29;12:21526567211045041. doi: 10.1177/21526567211045041. eCollection 2021 Jan-Dec.
Aging-related olfactory loss is associated with olfactory stem cell transcriptional alterations in humans
J Clin Invest. 2022 Feb 15;132(4):e155506. doi: 10.1172/JCI155506.
Sinus headache: changing the treatment paradigm
Curr Opin Otolaryngol Head Neck Surg. 2022 Feb 1;30(1):63-67. doi: 10.1097/MOO.0000000000000779.
Persistent post-COVID-19 smell loss is associated with immune cell infiltration and altered gene expression in olfactory epithelium
Sci Transl Med. 2022 Dec 21;14(676):eadd0484. doi: 10.1126/scitranslmed.add0484. Epub 2022 Dec 21.
Nasal Cavity Squamous Cell Carcinoma: Factors Associated With Treatment Outcomes and Potential Organ Preservation
Am J Rhinol Allergy. 2023 Jan;37(1):35-42. doi: 10.1177/19458924221130133. Epub 2022 Oct 2.
Rapid tissue prototyping with micro-organospheres
Stem Cell Reports. 2022 Sep 13;17(9):1959-1975. doi: 10.1016/j.stemcr.2022.07.016. Epub 2022 Aug 18.
Endoscopic Sinus Surgery in Older Patients With Significant Medical Comorbidities
Am J Rhinol Allergy. 2022 Sep;36(5):661-667. doi: 10.1177/19458924221101438. Epub 2022 May 16.
Persistent post-COVID-19 smell loss is associated with inflammatory infiltration and altered olfactory epithelial gene expression
bioRxiv. 2022 Apr 18:2022.04.17.488474. doi: 10.1101/2022.04.17.488474. Preprint.
Preoperative Embolization Techniques in the Treatment of Juvenile Nasopharyngeal Angiofibroma: A Systematic Review
Otolaryngol Head Neck Surg. 2023 Sep;169(3):454-466. doi: 10.1002/ohn.303. Epub 2023 Feb 17.
Barosinusitis due to routine weather changes: A cross-sectional analysis of public websites
World J Otorhinolaryngol Head Neck Surg. 2023 Jun 19;10(1):18-23. doi: 10.1002/wjo2.106. eCollection 2024 Mar.
Treatment of unilateral olfactory neuroblastoma: Appropriate extent of surgical resection and potential for olfactory preservation
Int Forum Allergy Rhinol. 2024 Mar 25. doi: 10.1002/alr.23345. Online ahead of print.
Predictors of Non-Rhinogenic Facial Pain or Pressure in Otolaryngology Clinic
Otolaryngol Head Neck Surg. 2024 Jan 14. doi: 10.1002/ohn.644. Online ahead of print.
You Do Not Rise to the Level of Your Goals; You Fall to the Level of Your Systems
Am J Rhinol Allergy. 2024 Jan;38(1):4-5. doi: 10.1177/19458924231217137.
Nasopharyngeal Carcinoma: Case Presentation and Literature Review of Treatment Innovation with Immunotherapy
J Neurol Surg Rep. 2023 Sep 27;84(3):e113-e115. doi: 10.1055/s-0043-1774333. eCollection 2023 Jul.
Preparation of Human Olfactory Epithelial Biopsies for Downstream Analysis
Methods Mol Biol. 2023;2710:121-129. doi: 10.1007/978-1-0716-3425-7_10.
Use of Tympanostomy T-Tube for Endoscopic Endonasal Marsupialization of Small Rathke's Cleft Cysts: A Case Series
J Neurol Surg B Skull Base. 2022 Aug 9;84(4):401-404. doi: 10.1055/s-0042-1755572. eCollection 2023 Aug.
Deconstructing Olfactory Epithelium Developmental Pathways in Olfactory Neuroblastoma
Cancer Res Commun. 2023 Jun 6;3(6):980-990. doi: 10.1158/2767-9764.CRC-23-0013. eCollection 2023 Jun.
Safety and Feasibility of Steroid-Eluting Stent as a Bolster in Endoscopic Anterior Skull Base Reconstruction
Ann Otol Rhinol Laryngol. 2024 Jan;133(1):43-49. doi: 10.1177/00034894231181178. Epub 2023 Jun 19.
Characterizing Olfactory Dysfunction in Patients with Unilateral Cleft Lip Nasal Deformities
Facial Plast Surg Aesthet Med. 2023 Nov-Dec;25(6):457-465. doi: 10.1089/fpsam.2022.0367. Epub 2023 May 2.
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